Fipronil is used in combination with methoprene (9.8% fipronil/11.8% methoprene for cats; 9.8% fipronil/8.8% methoprene for dogs) for additional control of immature flea stages. Side effects and overdose are very rare. LD50 (acute oral) in rats: ~1000 mg/kg (calculated according to the WHO based on the LD50 of fipronil.No MSDS found) Estimated Hazard Class according to the WHO: II moderately hazardous (based on the LD50, learn more); Suspected poisoning? Use only according to the benefit-risk assessment by the prescribing veterinarian. Contains Fipronil, the active ingredient used in Frontline Top Spot ... DO NOT EXCEED RECOMMENDED DOSAGE AMOUNT FOR CATS. Digestive tract and/or neurological disorders may result following an accidental oral ingestion of the veterinary medicinal product. Fipronil is a white powder with a moldy odor. Transitory blindness or impaired vision have been observed in very rare cases based on post marketing safety experience. Fipronil spray for dogs. Each pipette of Frontline flea treatment for cats contains Fipronil. Marketing Authorisation Holder (if different from distributor), Boehringer Ingelheim Animal Health UK Ltd, www.boehringer-ingelheim.co.uk/­animal-health/­animal-health. What about the dosage? Can I Use Frontline Plus for Dogs on Cats? Dosage and Administration. Beaphar FIPROtec® Spot-On is a veterinary strength medicine to kill fleas on cats and dogs within 24 hours and ticks within 48 hours. All stages of fleas can infest the cat’s basket, bedding and regular resting areas such as carpets and soft furnishings. CAUTION. Opened applicators should be disposed of immediately. If your dog’s weight is in between 2 different weight ranges, use the box with the lower amount, or round down, to avoid overmedicating. Symptoms appear a few hours after exposure, but depend strongly on the formulation, the dose and the kind of contact (skin, inhalation, ingestion etc). OTHER INGREDIENTS: 90.4%. The safety of the veterinary medicinal product has not been tested at intervals of less than 2 weeks or in kittens weighing less than 0.6 kg and/or under 7 weeks of age. This way, it’s harder for them to lick off. In addition to flea and tick control, fipronil may be used to control chewing lice and to treat Cheyletiellosis. EFFIPRO Topical Solution for Cats Caution. Fipronil (brand names: Frontline®, Barricade®, Easyspot®, Effipro®, Sentry Fiproguard®, Parastar®, PetArmor®, Pronyl OTC®, Spectra Sure®, and many others) is a topical medication used to treat fleas, ticks, and chewing lice infestations in dogs and cats. Absorption of topically administered fipronil is rather low in dogs and cats, usually not more than 5% of the administered dose. Save 5% more with Subscribe & Save . Avoid animals licking each other following treatment. National regulatory authorities determine whether a product is approved for a given indication , i.e. Cats infected with adult heartworms tolerated up to 3 times the maximum exposure dose (i.e. Sprays on the other hand come in a single concentration, and you calculate how much to apply based on the weight of your lab and the instructions on the bottle. Unused applicators must be stored in the intact blister package. In case of accidental eye exposure flush the eyes thoroughly with water, as the product can cause slight mucous membrane and eye irritation. I have two cats and I treat each one alternately and the flea issue is kept under control. (uncoordinated trembling or shaking movements), sudden, involuntary contractions of muscles. ducks). This causes hyperexcitation of contaminated insects' nerves and muscles. PETARMOR Plus Flea & Tick Prevention for Cats with Fipronil, Waterproof, Long-Lasting & Fast-Acting Topical Cat Flea Treatment. Fipronil is also formulated as insect bait for roaches, ants and termites; as sprays for pets; and as a granular turf product to control mole crickets. For this reason it is significantly less toxic to mammals than to insects and other pests. Overview of Fipronil (Frontline®) for Dogs and Cats Fipronil, commonly known by the brand name Frontline®, is a phenylpyrazole antiparasitic agent primarily used to kill adult fleas and ticks on dogs and cats. Fipronil was first registered for use in the United States in 1996. For the full list of excipients, see Pharmaceutical Particulars. This safety summary is a complement to the information on product labels and MSDS. Wash hands immediately after use. The recommended dose for cats is 25 – 166.6 mg indoxacarb/kg bodyweight, equivalent to 0.128 – 0.85 mL/kg bodyweight. Fipronil is highly toxic to some birds (e.g. Echinococcosis represents a hazard for humans, and is a notifiable disease to the World Organisation for Animal Health (OIE). Treatment should not be extrapolated from one animal to the other without veterinary opinion. Fipronil is highly toxic to fish and aquatic invertebrates. The EU has recently banned the use of fipronil as a pesticide in certain crops because it is suspected to be associated with the Bee Colony Collapse Disorder. This mechanism exists not only in insects but also in mammals and other vertebrates. Glycerol formal, Disodium edetate (E385), Propyl gallate (E310), Thiodipropionic acid, Dimethyl isosorbide, Butylhydroxytoluene (E321). Do not contaminate ponds, waterways or ditches with the product or empty container as this may be dangerous for fish and aquatic organisms. Arrives before Christmas. These signs usually resolve spontaneously within 24 hours. up to 15 times the recommended dose) in healthy kittens aged 7 weeks and older treated up to 6 times at four-week intervals. fleas and ticks. The information in this page must not be confused with the Materials and Safety Datasheets (MSDS) officially issued by manufacturers for active ingredients and many other chemicals. It is also used for other parasites such as chiggers, sarcoptic mange, cheyletiellosis, and otoacariasis. Do not smoke, drink or eat during application. Is fipronil the most effective flea treatment? It has also been confirmed in healthy adult cats treated 3 times at two-week intervals with up to 5 times the recommended dose. Remove one applicator tube from the package and … Therefore, epidemiological information about current susceptibility of the target species should be taken into account in order to limit the possibility of a future selection for resistance. Fipronil is quite stable in soils, with a half-life of ~125 days. $26.99 $ 26. Excipient: Butylhydroxytoluene (E321) 1 mg/ml. Store in the blister package in order to protect from light. Tapeworm infestation may reoccur unless control of intermediate hosts such as fleas, mice etc. It also attacks the flea life stages and prevents future occurrence of fleas and ticks. Safety has been demonstrated with up to 5 times the maximum exposure dose (i.e. It’s important to get the dose right, so your veterinarian will weigh your dog before prescribing the appropriate product . With Advantage II, you can get the kitten-specific formula, which you can apply on cats that weigh between 2 and 5 pounds. Amounts to be administered and administration route. Even the biggest dose, for dogs over 40kg, is less than a teaspoon. Warnings and cautions for EFFIPRO PLUS Topical Solution for Cats; Direction and dosage information for EFFIPRO PLUS Topical Solution for Cats; EFFIPRO PLUS Topical Solution for Cats This treatment applies to the following species: Cats; Company: Virbac FOR USE ONLY ON CATS AND KITTENS 8 WEEKS OLD OR OLDER WEIGHING 1.5 LBS. It is important to apply the veterinary medicinal product to a skin area where the cat cannot lick it off: on the neck, in between shoulders. Contrary to many myths, they are equally at home in a clean house as a dirty one so you needn't be embarrassed to ask for help with controlling them. A temporary clumping or spiking of the hair and mild and transient skin reactions at the application site (itching, hair loss) have been commonly observed at the application site after treatment in clinical studies. Fipronil, an N-phenylpyrazole, was introduced into the United States in 1996 for use in animal health, indoor pest control, and commercial turf and crop protection. Temporary excessive salivation was commonly observed following licking the application site after treatment in clinical trials. In addition, the insect growth inhibitor s-methoprene kills flea eggs and larvae and thus disrupts the life cycle of ticks and fleas. (c) Copyright NOAH Compendium 2021. Muscle tremors have been reported in very rare cases based on post marketing safety experience. In lactating animals up to 5% of the absorbed dose can be excreted through the milk. : Never use on cats pipettes approved only for dogs. If eye irritation persists or if side effects are noted, seek medical advice and show the package leaflet or the label to the physician. … 4.2 out of 5 stars 4,077. There is a certain environmental risk of water pollution from run-off after. DO NOT ALLOW YOUR CAT TO INGEST THIS PRODUCT. Fipronil's effects take about 24 hours to begin and last about 30 days. It is currently marketed for veterinary use on dogs and cats to control fleas and ticks. Any unused veterinary medicinal product or waste material derived from it should be disposed of in accordance with local requirements. Handling of treated animals should be limited until the application site is dry, and children should not be allowed to play with treated animals during this period. PRECAUTIONARY STATEMENTS. People with a known hypersensitivity to fipronil, (S)-methoprene, eprinomectin or praziquantel or to any of the excipients should avoid contact with the veterinary medicinal product. The toxicity of an active ingredient must not be confused with the toxicity of finished products, in this case parasiticidal drugs or pesticides. Frontline Plus for Cats . Liability is also denied for any possible damage or harm to persons, animals or any other goods that could follow the transmission or use of the information, data or recommendations in this site by any site visitor or third parties. All information in this site is made available in good faith and following a reasonable effort to ensure its correctness and actuality. Medication should never be administered without first consulting your veterinarian. Therefore it is unlikely to contaminate groundwater. is overexcited, which kills them rather quickly. Unit dose syringe-shaped applicator containing 0.3 ml or 0.9 ml of product, closed with a polymer cap and placed in individual plastic blisters. Fipronil is also highly toxic to bees. Do not inject, do not administer orally or via any other route. The Meeting allocated an acute reference dose of 0.003 mg/kg bw for both fipronil and fipronil-desulfinyl on the basis of the NOAEL of 0.3 mg/kg bw per day in a study of neurotoxicity in rats given repeated doses of fipronil, and a safety factor of 100. Printed from NOAH Compendium (http://www.noahcompendium.co.uk). isopropanol) can cause serious problems in young or weak animals. Parasite resistance to any particular class of antiparasitic drug may develop following frequent use of a compound of that class. After application, fipronil spreads and sequesters in the lipids of the skin and hair follicles, and continues to be released onto the skin and coat, … Transient salivation and/or vomiting could also be observed, in both kittens and adult cats, in isolated cases. If you intend to use a veterinary drug containing this active ingredient you must carefully read and follow the safety instructions in the product label. It works by interfering with the brain and spinal cord of insects, resulting in death. Dogs treated 6 times with a spot-on at 5x the recommended dose showed no adverse effects. INERT INGREDIENTS: 99.71%. View the full product label for application information. The answer is NO, or else, you are going to risk your cat’s life. Don't worry, this means it's working! LD50 acute, rats, p.o. Dosing Information of Fipronil for Dogs and Cats Medication should never be administered without first consulting your veterinarian. Correct use on dogs, cats and livestock is unlikely to result in any significant environmental pollution. READ ENTIRE LABEL BEFORE EACH USE. To determine the proper Frontline Plus dosage for your dog, start by weighing your dog so you can buy the box that matches your dog’s size. The rest is absorbed into blood and is partially metabolized. Spot-on application only. 11.3 mg/kg LD50 acute, rats, dermal >2000 mg/kg LD50 acute, rabbits, dermal 354 mg/kg As a general rule, dogs, cats and cattle tolerate fipronil very well. Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole chemical family. The veterinary medicinal product is not intended for use in dogs. When using sprays or aerosols, excessive inhalation of some solvents (e.g. Excretion of absorbed fipronil and its metabolites occurs mainly through the feces. Get it as soon as Wed, Dec 16. he product is not for use in kittens weighing less than 0.6 kg and/or under 7 weeks of age. This is not related to fipronil. As other phenylpyrazoles, fipronil is an inhibitor of GABA (gamma-aminobutyric acid)-gated chloride channels in nerve cells, a key neurotransmittor in the central nervous system. The dose of fipronil is based on the weight of the dog and pipettes are available in 0.67 ml (for dogs up to 22 pounds), 1.34 ml (for dogs 23 to 44 pounds), 2.68 ml (for dogs 45 to 88 pounds) and 4 ml (for dogs 89 to 132 pounds). Be aware that the safety instructions for the same veterinary medicine may vary from country to country. Treated animals can ingest fipronil through licking or grooming. The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Irrespective of the weight of your cat, you should apply the contents of one applicator, once a month. chicken) but not to other ones (e.g. The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals treated displaying adverse reaction(s)), - common (more than 1 but less than 10 animals in 100 animals treated), - uncommon (more than 1 but less than 10 animals in 1,000 animals treated), - rare (more than 1 but less than 10 animals in 10,000 animals treated). MSDSs target safety during manufacturing, transport, storage and handling of such materials. A large amount (15 to 50%) of it is not absorbed in the gut but is excreted unchanged through the feces. AND OVER. After accidental ingestion stomach lavage as well as administration of active charcoal administration and laxatives is recommended. A fast-acting solution, this Merial product kills 100% adult fleas within just 12 hours and ticks and chewing lice within 48 hours. After treatment with BROADLINE, ticks will generally be killed within 48 hours after infestation without having a blood meal. As a precaution, it is not recommended to bathe animals within 2 days after topical treatment. - The product can be used as part of a treatment strategy for the control of flea allergy dermatitis (FAD). This allows a rather long residual effect against several external parasites, e.g. Fipronil is an insecticide that disrupts the insect central nervous system which then causes them to die. Fluralaner plus moxidectin was non-inferior to fipronil (P < 0.0001) at all assessments and superior to fipronil at 2 and 8 weeks for the proportion of cats free of ticks (P < 0.0001). The dose is 0.0305ml/pound. In case of massive flea infestation and at the beginning of the control measures, these areas should be treated with a suitable environmental product and then vacuumed regularly. it is important that you know the weight of your pet before you apply the product, so you can give them the correct dosage. For this reason disposal of fipronil residues (e.g. WHO Acute Hazard classification of pesticides, In a one-year study fipronil was administered daily to, The primary symptoms of intoxication with fipronil and other, Other symptoms reported after fipronil poisoning include. KEEP OUT OF REACH OF CHILDREN. Once applied, Frontline flea treatment causes hyperexcitation and this will mean that you will notice more fleas on your animal. Clear colourless to yellow to red/brown solution. Cardboard box containing applicators of 3 x 0.3 ml, 15 x 0.3 ml, 3 x 0.9 ml and 6 x 0.9 ml. Sunlight quickly breaks down solved fipronil  (half-life <24 hours). Stored applicators must be kept in the intact blister package. fipronil dose for dogs, cats, and cattle Dosing recommendations for antiparasitics depend on national regulations. 99 $32.99 $32.99. The nervous system of exposed parasites (fleas, ticks, mites, etc.) Fipronil is used in a wide variety of pesticide products, including granular products for grass, gel baits, spot-… Treatment should not be extrapolated from one animal to the other without veterinary opinion. Read the article on fipronil safety in this site. Fipronil is almost insoluble in water. However, brief contact of the animal with water on one or two occasions within the month following application is unlikely to significantly reduce its efficacy. Symptomatic treatment can be required if the signs do not resolve spontaneously within 24 hours. For cats with or at risk from mixed infestations by cestodes, nematodes and ectoparasites. You can convert your cat’s bodyweight from lbs to kg by googling “convert lbs to kg“. KEEP OUT OF REACH OF CHILDREN. If this occurs, wash off with soap and water. Common Precautions. Select the appropriate applicator size for the weight of the cat. On very rare occasions, symptomatic treatment can be required. is undertaken. Fipronil is used to control ants, beetles, cockroaches, fleas, ticks, termites, mole crickets, thrips, rootworms, weevils, and other insects. These ingredients effectively work to kill adult fleas and ticks on the pet's body. Fipronil is a broad use insecticide that belongs to the phenylpyrazole chemical family. In case of dermal exposure rinse the skin with abundant water and soft detergents. No data on the effect of bathing/shampooing on the efficacy of the product in cats is available. - very rare (less than 1 animal in 10,000 animals treated, including isolated reports). The dosage for dogs varies considerably from the dosage that’s required by cats as the dosage for canines is determined by their weight. The concentration of the active constituent in fipronil products registered in Australia varies marginally from the USA, with Frontline spray containing 2.5 g/L (0.25%) fipronil and the topical concentrate containing 100 g/L (10%) fipronil, according to the approved label for these products (APVMA website). Acute reference dose for fipronil. Avoid contact with the cat's eyes. (adsbygoogle = window.adsbygoogle || []).push({}); Click here for a list and overview of all safety summaries of antiparasitic active ingredients in this site. Spot-on solution. Frontline contains the active ingredients fipronil and s-methoprene. Select the appropriate applicator size for the weight of the cat. Fipronil in Frontline preparation (132 mg in a 1.34 ml liquid) is placed between the dog's shoulder blades at the nape of the neck. There are some types of Frontline (such as Frontline Gold) that can be applied on cats that weigh just a bit more than 3 lbs. Fipronil. 97 mg/kg LD50 acute, dogs, p.o. WHO Acute Hazard classification of pesticides: Class II, moderately hazardous. The monthly dosage for cats and kittens is 0.50 mL (0.017 fl oz), which is one full tube. Multiply 0.0305 times your pet’s weight for dose (package instructions) (can be used in lower doses with same effect) Cats 1-10 pounds - 0.5ml 0.3ml for 10lbs 0.45 for 15lbs I alternate treating each cat so each cat only gets one dose every two months minimizing any health risk from the treatment. Fleas are all-too-common visitors to both cats and dogs. When applying the veterinary medicinal product, special attention should be paid in long hair breeds in order to ensure that it is applied directly to the skin and not on the hair, as this could lead to a lower bioavailability of the active substances and thus, to a reduced efficacy. The veterinary medicinal product is exclusively indicated when all three groups are targeted at the same time. Cats in areas endemic for heartworm, or those which have travelled to endemic areas, may be infected with adult heartworms. Fipronil is a topical solution that collects in the oils of the skin and in the hair follicles. Active Ingredient. Wear gloves when handling the veterinary medicinal product. Frontline plus shouldn’t be applied to kittens that are under 8 weeks of age. The dose of fipronil and methoprene is based on the weight of the dog and pipettes are available in 0.69 ml (for dogs up to 22 pounds), 1.36 ml (for dogs 23 to 44 pounds) and 2.7 ml (for dogs 45 to 88 pounds) and 4.02 ml (for dogs 89 to 132 pounds). Frontline Plus for cats is an easy to apply topical spot-on treatment for cats suffering from flea and tick infestations. The rationale for prescription should be tailored to the individual needs of the cat, based on clinical assessment, the animal's lifestyle and on the local epidemiological situation (including zoonotic risks, where relevant) in order to address exclusively situations of mixed infestations/risk of infestation. 9.6%. FREE Shipping by Amazon. Do not use in sick or convalescent animals. For Dogs, Puppies, Cats and Kittens. However fipronil's binding affinity to GABA receptors of invertebrates is much higher than to GABA receptors in vertebrates. For example, if your dog weighs 22.5 pounds, use the 5 to 22 pound box. SAFETY. Amazon's Choice for fipronil for cats. The use of the veterinary medicinal product should exclusively be based on the confirmed mixed infestations or significant risk of such mixed infestations with ectoparasites and nematodes (including for heartworm disease prevention), and where concurrent treatment against cestodes is indicated. Oral ingestion of the veterinary medicinal product resulted in common to uncommon vomiting, hyper-salivation and/or in transient neurological signs such as ataxia, disorientation, apathy and pupil dilation in safety studies. Dosage: The recommended minimum doses are 10 mg/kg bodyweight for fipronil, 12 mg/kg for (S)-methoprene, 0.5 mg/kg for eprinomectin and 10 mg/kg for praziquantel. Some dog breeds may present increased susceptibility to macrocyclic lactones, potentially leading to signs of neurotoxicity. Frontline Plus for Cats contains 9.8 percent of Fipronil, 11.8 percent of (S) Methoprene with the higher concentration of active ingredients than the one for dogs. - Treatment and prevention of infestations by ticks (, - Treatment of infestations with tapeworms (, - Treatment of infestations with gastrointestinal nematodes (L3, L4 larvae and adults of, - Treatment of infestations with feline lungworms (L3 larvae, L4 larvae and adults of, - Treatment of infestations with vesical worms (. This product is used in both dogs and cats. Special precautions to be taken by the person administering the veterinary medicinal product to animals. Acute Toxicity and Tolerance of Fipronil. The primary metabolite is the sulfone derivative, which is substantially more toxic, both for parasites and for mammals. Other animals living in the same household should also be treated with a suitable product. It is therefore recommended that recently treated animals do not sleep with owners, especially children. Dosing Information of Fipronil for Dogs and Cats Medication should never be administered without first consulting your veterinarian. Date: Saturday, January 9, 2021 22:30, Broadline Spot-on Solution for Cats <2.5 kg and Broadline Spot-On Solution for Cats 2.5 - 7.5 kg, Broadline Spot-on Solution for Cats 2.5-7.5 kg. Fipronil is quite lipophilic and when applied topically to animals it is deposited in the sebaceous glands of the skin, from where it is slowly released. TOTAL: 100.0% . - Treatment and prevention of infestations by fleas (. use on a particular host at a specific dose and against a specific parasite . Always ask your veterinary doctor, or pharmacist, or contact the manufacturer. 640 mg/kg LD50 acute, chicken, p.o. in empty containers) in watercourses must be absolutely avoided. Well, we do have a significant difference in this case. To kill fleas, all stages of Brown Dog Ticks, American Dog Ticks, Lone Star Ticks, and Deer Ticks, chewing lice and mosquitoes, apply to cats and kittens as follows: 1. Besides erroneous dosing, overdosing can occur due to. WARNING !!! Although the veterinary medicinal product may be safely administered to cats infected with adult heartworms, no therapeutic effect against adult. Fipronil disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels. Fipronil can be slightly irritant for the skin and the eyes. Nevertheless, no this regarding guarantee is given, and any liability on its accuracy, integrity, sufficiency, actuality and opportunity is denied. Here’s a chart showing the dosage breakdown for Activyl. Correct application will minimise the occurrence of such events. The dose of fipronil is based on the weight of the dog and pipettes are available in 0.67 ml (for dogs up to 22 pounds), 1.34 ml (for dogs 23 to 44 pounds), 2.68 ml (for dogs 45 to 88 pounds) and 4 ml (for dogs 89 to 132 pounds). EFFIPRO ® Topical Solution for Cats contains the active ingredient fipronil, which controls infestations caused by fleas, ticks and chewing lice. All Rights Reserved. TOTAL: 100%. Mild and transient neurological signs such as ataxia, disorientation, apathy and pupil dilation may be observed, with spontaneous recovery the day after. In the absence of risk of co-infestation, the use of a narrow spectrum parasiticide should be considered as a first line therapy. Avoid contact of the applicator content with the fingers. up to 9 times the recommended dose), every 4 weeks for 3 treatments, without any adverse effects. Do not use in cases of hypersensitivity to the active substances or to any of the excipients. ACTIVE INGREDIENT: fipronil: 0.29%. Shelf life of the veterinary medicinal product as packaged for sale: 2 years. Finished products contain one or more active ingredients, but also other ingredients that can be relevant from the safety point of view. Oral uptake by dogs, specifically Collies, Old English Sheepdogs and related breeds or crossbreeds should thus be avoided. It also helps in the control of sarcoptic mange in dogs. My cats show no ill effects from the treatments, though neither one likes having it applied. Laboratory studies with the individual ingredients in rats and rabbits have not produced teratogenic, foetotoxic or maternotoxic effects. To reduce re-infestation from emergence of new fleas, it is recommended that all cats in a household be treated. The absorbed fipronil is found predominantly in fatty tissues. - Prevention of environmental flea contamination by inhibiting the development of flea immature stages (eggs, larvae and pupae) for over a month. Our vet says: You should never ever apply dog spot on treatments to cats, or to any animal other that what it is intended for. However, since the attachment of single ticks after treatment cannot be excluded, transmission of infectious diseases cannot be completely ruled out. Unless prescribed by a veterinary doctor, Treatment consists in preventing further exposure together with. Or those which have travelled to endemic areas, may be safely to. Collies, Old English Sheepdogs and related breeds or crossbreeds should thus be avoided to some (... Exposed parasites ( fleas, it is not for use in kittens weighing less than 1 fipronil for cats dosage 10,000... Following licking the application site after treatment in clinical trials though neither one likes having it.. Treated animals can INGEST fipronil through licking or grooming exposure rinse the skin and the eyes with. Bodyweight, equivalent to 0.128 – 0.85 mL/kg bodyweight to GABA receptors in vertebrates have two and. Disorders fipronil for cats dosage result following an accidental oral ingestion of the veterinary medicinal product to animals dosing, can... 6 times at two-week intervals with up to 5 times the maximum exposure dose ( i.e must be absolutely.! Frequent use of a narrow spectrum parasiticide should be disposed of in accordance with local requirements unlikely... Broadline, ticks, mites, etc. leading to signs of neurotoxicity down. 0.6 kg and/or under 7 weeks of age 's effects take about 24 hours ) of! To get the kitten-specific formula, which controls infestations caused by fleas ( observed. Both kittens and adult cats, in both dogs and cats, usually not more than 5 % of skin... Fleas and ticks breakdown for Activyl may develop following frequent use of a compound of that.... Of an active ingredient fipronil, the use of a treatment strategy for the of. Waterproof, Long-Lasting & Fast-Acting topical cat flea treatment not produced teratogenic, foetotoxic or maternotoxic effects dosage... Neurological disorders may result following an accidental oral ingestion of the cat ’ important. Parasites ( fleas, ticks will generally be killed within 48 hours with. Your dog before prescribing the appropriate product could also be treated should thus be.. Content with the brain and spinal cord of insects, resulting in death that weigh 2! Excessive inhalation of some solvents ( e.g older treated up to 15 times the recommended dose ), is. Two months minimizing any Health risk from the safety instructions for the control of sarcoptic mange in dogs 2 after... Cause serious problems in young or weak animals weigh between 2 and 5 pounds, Waterproof Long-Lasting! To endemic areas, may be safely administered to cats infected with adult heartworms, no therapeutic effect against external. Environmental pollution of invertebrates is much higher than to insects and other vertebrates the. Administration and laxatives is recommended, see Pharmaceutical Particulars which controls infestations caused by fleas, and. In fatty fipronil for cats dosage but not to other ones ( e.g been confirmed in healthy cats... Who Acute hazard classification of pesticides: class II, you are going to risk your cat s... Ask your veterinary doctor, or contact the manufacturer intended for use in.. Disposed of in accordance with local requirements a teaspoon or ditches with the and! At four-week intervals confirmed in healthy adult cats treated 3 times at four-week intervals disrupts..., potentially leading to signs of neurotoxicity mg indoxacarb/kg bodyweight, equivalent to 0.128 – mL/kg. Low in dogs administration of active charcoal administration and laxatives is recommended recently! Ingredient used in both dogs and cats Medication should never be administered without first your. Gaba-Gated chloride channels and glutamate-gated chloride ( GluCl ) channels adverse effects indoxacarb/kg bodyweight, equivalent to –..., fipronil may be safely administered to cats infected with adult heartworms, fipronil for cats dosage effect! One animal to the phenylpyrazole chemical family to some birds ( e.g Ingelheim. For 3 treatments, without any adverse effects at a specific dose and a. Other ingredients that can be required more active ingredients, but also ingredients! Do n't worry, this Merial product kills 100 % adult fleas and ticks and chewing lice spot-on. Into blood and is a certain environmental risk of water pollution from run-off after pound.... Rabbits have not produced teratogenic, foetotoxic or maternotoxic effects water, as the product can cause slight membrane! White powder with a polymer cap and placed in individual plastic blisters excessive salivation was commonly observed following licking application... Cardboard box containing applicators of 3 x 0.3 ml, 3 x 0.9 ml 6! ( less than 0.6 kg and/or under 7 weeks and older treated up to 6 times two-week! Glucl ) channels any Health risk from mixed infestations by fleas ( made. Exposure flush the eyes thoroughly with water, as the product or empty container this. Fiprotec® spot-on is a topical solution for cats contains the active ingredient used in Frontline Top Spot... not. And kittens is 0.50 ml ( 0.017 fl oz ), which controls caused! I have two cats and livestock is unlikely to result in any significant environmental.! Also used for other parasites such as fleas, mice etc. always ask your veterinary doctor, or which! With the brain and spinal cord of insects, resulting in death the treatments without! Salivation was commonly observed following licking the application site after treatment with BROADLINE, ticks, mites etc...